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ACP - 50mg
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248.00 EUR
Model: NOX-04.1-50mg
Manufactured by: Noxygen
Synonym:
1-Acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine
Appearance:
White Solid
Chemical Structure:
C
11
H
20
N
2
O
3
MW:
228.3
Purity:
99%
Solubility:
Soluble in water, DMSO, methanol or ethanol
Storage:
-20°C
Add to Cart:
ACP
Effective spin probe for the
EPR imaging
and
in vivo
detection of intracellular
ROS (superoxide, peroxynitrite etc.). ACP can be easily protected with esterase to yield cyclic hydroxylamine, which can be oxidized by reactive oxygen species to yield ESR-detectable nitroxide radicals. The nitroxide radical is resistant to reduction by vitamin C and thiols.
Half-life time of nitroxide radical in biological environment up to 4h.
Samples in frozen condition (-80 °C or liquid nitrogen) can be stored
up to 6 months
.
Rerferences
H. Yokoyama, et al.; In vivo EPR imaging by using an acyl-protected hydroxylamine to analyze intracerebral oxidative stress in rats after epileptic seizures: Magn. Reson.
Imaging 18, 875 (Abstract)
Current Reviews: 0
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