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PPH - 100mg

504.00 EUR
99 Units in Stock
Model: NOX-03.2-100mg
Manufactured by: Noxygen
 
Synonym: 1-Hydroxy-4-phosphono-oxy-2,2,6,6-tetramethyl-piperidine
Appearance: White Solid
Chemical Structure: C9H20NO5P3
MW: 253.2
Purity: > 99% - contains traces of HCI
Solubility: Soluble in water, DMSO, methanol or ethanol
Storage: -20°C

PPH
Effective, non-cell permeable and non-toxic spin probe for detection of extracellular
in vitro and in vivo and mitochondrial
production of ROS (O2-, ONOO-). Resistant
against reduction of vitamin C or thiols. Half-life time of spin adduct in biological
environment amount to 4h. Samples in frozen condition (-80 °C or liquid nitrogen)
can be stored up to 6 months.

Rerferences

  1. Panov A. et al., Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication. J Biol Chem.: 2005, 280: 42026-35 (PDF)
  2. Dikalova A. et al., Noninvasive diagnostic tool for inflammation-induced oxidative stress using electron spin resonance spectroscopy and an extracellular cyclic hydroxylamine. Arch Biochem Biophys: 2002; 15;402:218-26. (PDF)
  3. Fink B. et al., A new approach for extracellular spin trapping of nitroglycerin-induced superoxide radicals both in vitro and in vivo. Free Radic Biol Med. 2000 Jan 1;28(1):121-8. (PDF)

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