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DETC - 5g

84.00 EUR
Model: NOX-10.2-5g
Manufactured by: Noxygen
Synonym: Diethyldithiocarbamic acid sodium salt
Appearance: White Solid
Chemical Structure: C5H10NNaS2· 3H2
MW: 225.31
Purity: 99%
Solubility: Water
Storage: -20°C

Biochem/physiol Actions Inhibits induction of macrophage nitric oxide synthase.
Application Spin trap used in conjunction with Fe2+to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
Miscellaneous Reagent used for the extraction of trace metals into organic solvents for atomic absorption spectroscopy; Precipitation of trace metals for X-ray fluorescence spectroscopy
  • K.L. Cheng et al.,Handbook of Organic Analytical Reagents Boca Raton, p. 389 (1982)
  • W. Klemm et al.,Fres. Z. Anal. Chem. 364, 429 (1999)
  • S. Br├╝ggerhoff et al.,Fres. Z. Anal. Chem. 311, 252 (1982)
  • Minakata, K., Quantification of copper in biological materials by use of electron spin resonance. Clin. Chem. 47, 1863 (2001)
  • Vanin, A.F., Iron diethyldithiocarbamate as spin trap for nitric oxide detection. Meth. Enzymol. 301, 269 (1999)
  • Wallis, G.,In vivospin trapping of nitric oxide generated in the small intestine, liver, and kidney during the development of endotoxemia: a time-course study. Shock 6, 274 (1996)
  • James, P.E., Simultaneous measurement of NO(*) and PO2from tissue byin vivoEPR. Nitric Oxide 3, 292 (1999)

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