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ACP - 100mg

302.00 EUR
100 Units in Stock
Model: NOX-04.2-100mg
Manufactured by: Noxygen
 
Synonym: 1-Acetoxy-3-carboxy-2,2,5,5-tetramethylpyrrolidine
Chemical Structure: C11H20N2O3
Appearance: White Solid
MW: 228.3
Purity: 99%
Solubility: Soluble in water, DMSO, methanol or ethanol
Storage: -20°C

ACP
Effective spin probe for the EPR imaging and in vivo detection of intracellular
ROS (superoxide, peroxynitrite etc.). ACP can be easily protected with esterase
to yield cyclic hydroxylamine, which can be oxidized by reactive oxygen species
to yield ESR-detectable nitroxide radicals. The nitroxide radical is resistant to
reduction by vitamin C and thiols. Half-life time of nitroxide radical in biological
environment up to 4h. Samples in frozen condition (-80 °C or liquid nitrogen)
can be stored up to 6 months .

Rerferences

  1. H. Yokoyama, et al.; In vivo EPR imaging by using an acyl-protected hydroxylamine to analyze intracerebral oxidative stress in rats after epileptic seizures: Magn. Reson. Imaging 18, 875 (Abstract)

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